She grew up in Arlington, Texas, a suburb of the Dallas – Fort Worth Metroplex area, where she attended Lamar High School. She was active in drama, band and student government. Bohrer has done cosmetic and swim suit modeling.

Bohrer's work has included a recurring role as Lianne Mars, the wayward mother of the title character in the CW television series Veronica Mars. Previous roles were more comedic, including her role as a pediatric nurse who had a crush on Elliot Gould in the short-lived CBS situation comedy E/R, a witch in the similarly brief ABC sitcom Free Spirit, an administrative assistant to a Los Angeles City Councilman played by James Garner in the quickly-cancelled NBC sitcom Man of the People, Prank in The Flash tv series and the mom of a harried movie megaplex worker in Disney's original movie Phantom of the Megaplex (2000). She also appeared as the love interest opposite Randy Quaid in Dead Solid Perfect, and featured in the Dream On episode "What I Did for Lust" and the Friends episode "The One Where Rachel Finds Out" (1995).

Over the years, Bohrer has also frequently appeared in commercials. Bohrer played the role of the "counselor" in Apple's "Get a Mac" ad campaign. More recently, she was in commercials for Totinos Pizza Rolls, Walgreens, Campbell's low sodium soup and Bounty ("One-sheeter"!).